ABSTRACT

In counselling patients about the benefits of pharmacologic therapy or other inter­ ventions to reduce bone loss and prevent fractures, physicians frequently make reference to the adverse outcomes of osteoporosis. These relate mainly to osteo­ porotic fractures. H ip and spine fractures are linked to increased mortality, and all fractures may lead to disability and reduced quality of life. Moreover, expenditures on the care o f these fractures are high. This chapter reviews recent reports on the burden of osteoporosis with respect to mortality, morbidity and cost.