ABSTRACT
Introduction: The Neuronal Network Responsible for Paradoxical Sleep before the Head-Restrained Rat Model ................................................................84
The PS Neuronal Network Identified with the Head-Restrained Rat Model.........86 Identification and Pharmacology of a Pontine PS-Inducing
Structure in Rats........................................................................................86 Efferents of the PS-On Neurons from the SLD..........................................89 GABAergic and Non-GABAergic Inputs to the SLD PS-On Neurons......90 Evidence That GABA Is Responsible for the Inactivation of
Monoaminergic Neurons during PS .........................................................93 Localization of the GABAergic Neurons Responsible for the Tonic
Inhibition of Monoaminergic Neurons during PS....................................96 Conclusion: A New Network Model for PS Onset and Maintenance....................97 Acknowledgments....................................................................................................98 References................................................................................................................98
In the middle of the last century, a series of historical observations led to the discovery of a sleep phase in humans and other mammals characterized by a cortical activation and conspicuous rapid eye movements (REM) paradoxically associated with a complete disappearance of the muscle tone.
