ABSTRACT
Introduction............................................................................................................123 Evidence for a Genetic Contribution to Sleep......................................................124 Candidate Gene Studies.........................................................................................125 Mutagenesis Studies ..............................................................................................126 Quantitative Trait Loci (QTL) Studies..................................................................127 QTL Analysis of Sleep Duration, Distribution, and Architecture ........................128 QTL Analysis of the Sleep EEG...........................................................................130 QTL Analysis of Homeostatic Regulation of Sleep .............................................131 Gene Expression Studies .......................................................................................132 Genetics of Circadian Rhythms ............................................................................134 Conclusions............................................................................................................137 Acknowledgments..................................................................................................138 References..............................................................................................................138
The behavior sleep is conserved across many species including birds and mammals. Sleep-like behavior has also been characterized in invertebrates,
