ABSTRACT
Factor Receptor (EGFR) and Expression of HER2/neu .....................................353 23.2.4 Curcumin Down-Regulates the Activation of Nuclear
Factor-
k
B (Nf-
k
B) ...............................................................................................354 23.2.5 Curcumin Down-Regulates the Activation of STAT3 Pathway ..........................354 23.2.6 Curcumin Activates Peroxisome Proliferator-Activated
Receptor-
g
(PPAR-
g
) ............................................................................................355 23.2.7 Curcumin Down-Regulates the Activation of Activator
Protein-1 (AP-1) and C-Jun N-Terminal Kinase (JNK) .....................................355 23.2.8 Curcumin Suppresses the Induction of Adhesion Molecules .............................355 23.2.9 Curcumin Down-Regulates Cyclooxygenase-2 (COX-2) Expression ................355 23.2.10 Curcumin Inhibits Angiogenesis..........................................................................356 23.2.11 Curcumin Suppresses the Expression of MMP9 and Inducible
Nitric Oxide Synthase (iNOS).............................................................................356 23.2.12 Curcumin Down-Regulates Cyclin D1 Expression .............................................356 23.2.13 Curcumin Is Chemopreventive ............................................................................356 23.2.14 Curcumin Inhibits Tumor Growth and Metastasis in Animals ...........................357 23.2.15 Curcumin Inhibits Androgen Receptors and AR-Related
Cofactors ..............................................................................................................358 23.3 Effect of Curcumin on Atherosclerosis and Myocardial Infarction ....................................359
