V. Validation and optimization Validation of clinical trial formulations Validation of in vitro tests on solid dosage forms Experimental strategy for validation of industrial processes Optimization of industrial processes by evolutionary operation (EVOP)


Using the methods of chapter 5 we can determine a (polynomial) model and use it to predict the value of a response over the whole of the experimental region. In addition to characterizing the process or system in general, we may use this mapping to find the best processing conditions and the best formulation.