ABSTRACT

346Many drug classes cause CNS stimulation when ingested in toxic amounts (Table 16.1). Traditionally, drugs, such as amphetamine and strychnine, produce strong convulsant activity. However, other drugs may act as moderate CNS stimulants. Stimulants represent a diverse group of compounds that are chemically and pharmacologically dissimilar. When ingested in moderate to high doses, they cause a variety of effects related to central nervous system excitation. Overdoses of this group are treated in much the same manner, with a few exceptions. Drug compounds with CNS<xref ref-type="fn" rid="tabfn16_1_a"> <sup> <italic>a</italic> </sup> </xref>-stimulant activity

Amphetamine

See Table 16.2

Anorexiants

See Table 16.2

Analeptics

Doxapram

Methylphenidate

Pentylenetetrazol

Picrotoxln

Strychnine

Xanthines

Caffeine

Theobromine

Theophylline

Local anesthetics

Camphor

Cocaine

Psychotomimetics

See chapter 17

CNS, central nervous system.