ABSTRACT

I. INTRODUCTION A, Historical Although the properties of ion exchangers, the fundamentals of the ion-exchange process, and the applications of ion-exchange toward the separation of inorganic and organic analytes were well understood [1-5; see Chap. 11], ion exchange and its applications in high-performance liquid chromatography (HPLC) were not widely practiced as high-efficiency LC was emerging as a major separation technique. This was particularly true in applications directed toward the separation of inorganic analyte ions.