Modulated Drug Therapy with Inhalation Aerosols: Revisited

A number of elegant devices have been developed in recent years that can deliver

an aerosol to the deep lungs with high efficiency, but what can be influenced after

deposition has occurred? Presently, there is little flexibility in aerosol

formulations that will allow for manipulation of in vivo performance, and

there remains an inadequate body of literature discussing the concept [1]. Despite

this situation there is certainly more than ample justification for pursuing the

topic, as specified in Table 1.