ABSTRACT

Each of the above conditions may exist separately or in various combinations. Undoubtedly other additive factors operate, but relative values are unreliable. Age, of itself, does not constitute a high risk.[1-3]

In decreasing order of frequency, factors in perioperative stroke are plaque and thrombus fragmentation during carotid dissection, with embolization to the intracranial circulation as

the artery is being exposed or otherwise manipulated; formation of thrombus on the highly thrombogenic endarterectomized segment with local and distal progression and possible embolization; ipsilateral hemispheric ischemia during interruption of carotid flow; and reduced carotid flow secondary to reduced cardiac output or hypotension of whatever cause.