ABSTRACT
Precise prediction of gene sites in a DNA sequence is a critical task in the area of bio-informatics. Accuracy in this prediction will be helpful in disease diagnosis and therapy. Gene identification focuses on identifying exon areas in a gene arrangement using algorithms of computational biology. After sequencing the genome of a species, one of the significant steps is to know the molecular nature of the genome. Nowadays, due to the availability of prevailing computational resources and also gene sequences of various species, exon prediction has largely become a crucial problem of computation for the community of research.
This chapter presents an overview of genomics engineering, structure of DNA sequence and its building blocks, flow of genetic information in a cell, gene prediction along with its significance, and various types of gene prediction methods (i.e. extrinsic, ab initio, and comparative). An account of the objectives of our research work and various types of DNA representations for genomic sequence analysis along with its desirable properties is provided, and lastly, the organization of the book is also described.
