ABSTRACT
This chapter discusses the TSE-BPT significance of CP in various pulmonary diseases. CP/ATG prevents or promotes the progression of pulmonary diseases by exerting its diverse functions, including regulation of cell proliferation, cell death, cell survival, and innate and adaptive immune responses. Recently, Hara et al. outlined the role of MQC systems in the pathogenesis of age-associated lung diseases, COPD, and idiopathic pulmonary fibrosis. Hence, antioxidants as CP regulators and apoptosis inhibitors can be developed for the TSE-EBPT of PH. The eradication of pathogenic microbes by CP/ATG, including M. tuberculosis, is an effective host immune process that protects hosts from developing diseases associated with intracellular pathogens. Mechanical ventilation is used to maintain life in patients with sepsis and sepsis-related acute lung injury (ALI), which may cause diaphragm weakness due to muscle injury and atrophy resulting in the development of ventilator-induced diaphragm dysfunction.
