ABSTRACT

All work with animals was conducted in the Comparative Medicine Department at Sanofi Genzyme (Framingham, MA, USA) in accordance with Institutional Animal Care and Use Committee standards. Both males and females of the two strains of mice used, C57BL/6NCrl and BALB/cAnNCrl mice, were obtained from Charles River Laboratories International, Inc. (Wilmington, MA, USA). Animals were euthanized by carbon dioxide asphyxiation prior to tissue removal and photography.