ABSTRACT

When considering the processes of immobilization of a-amino acids and peptides on polymers, one should primarily dwell on the synthesis of polypeptides using polymer carriers. Although the process of stepwise growth of the polypeptide polymer chain, according to this method, is beyond the scope of this monograph, note should be taken in this chapter of the binding of the first amino acid residue to the carrier. It is well known that the traditional methods of synthesis of peptides from low-molecular amino acids, that have formed over decades, made it possible to obtain a great number of compounds that contain a peptide group and have attracted the attention of researchers in the field of synthetic and physical chemistry, biochemistry, immunology, and pharmacology. Obtaining affinity sorbents is another important application of carrier-bound amino acids and peptides. Both unmodified amino acids and peptides and their derivatives were used.