ABSTRACT

Polymeric compounds of steroids — compounds containing a cyclopentano-perhydrophenanthrene system with hydroxyl and/or carbonyl groups — have drawn attention from the viewpoint of obtaining sorbents for affinity chromatography, as well as polymers with the qualities of liquid crystals and biologic activity. That some of them have an alcohol group explains why such steroids easily bind to a polymeric chain using, as a rule, the interaction of alcohol and acid chloride groups. Steroid polymers have been obtained through both polymerization of unsaturated derivatives and reactions of substitution of different carriers in the chain. Cholesteryl acrylate was copolymerized with N-acryloylpiperidine, while cholesteryl methacrylate with methyl methacrylate. Copolymerization of phenyl-p-acryloyloxy benzoate with cholesteryl acrylate, cholesteryl vinyl succinate and cholesteryl succinylethyleneglycol acrylate has been studied.