ABSTRACT
Necrosis and apoptosis are two distinct modes of cell death in nucleated eukaryotic cells. Programmed cell death (apoptosis) is an important mechanism of cell selection that acts as a molecular control end point regulating physiological processes, toxicities, and diseases through cell deletion. Although the mechanism involved in apoptosis differs in various cell types, it is characterized by distinct morphological and biochemical features such as the fragmentation of DNA. Exposure to low concentrations of xenobiotics or drugs can induce apoptosis.
