ABSTRACT

The cellular membrane is hypothetically the primary site

of interaction between cells and magnetic fields.[6-8]

Biological membranes possess a fundamental characteris-

tic structure described as the fluid mosaic model proposed

by Singer and Nicholson in 1972.[9] The membrane is

composed of a bilayer of phospholipids with embedded

functional proteins that play an important role in trans-

porting ions and other substances across the membrane.

Biological membranes exhibit an intrinsic anisotropic

structure and strong orientation in a magnetic field. In

homogeneous fields, orientation of the cell membranes-

parallel or perpendicular to the magnetic field-depends

on constituent proteins, and the degree of orientation

varies whenever phase transitions occur in the membrane.

In heterogeneous fields, a translational force acts on ani-

sotropic as well as on isotropic particles, depending on the

variation of the intensity across particles, on the excess

magnetic susceptibility of particles as compared to the

magnetic susceptibility of the surrounding medium, and

on particle volume.[10] The generation of metastable pores

in cell membranes is attributed to the presence of mag-

netic particles in the membrane, such as biologically

synthesized magnetite or contaminant particles. The