ABSTRACT
It is estimated that 76 million cases of food borne diseases
occur each year in the United States resulting in 325,000
hospitalizations and 5000 deaths, while the cost associated
to food-borne diseases, medical expenses, and productivity
losses in the United States is in the order of $6.6-37.1
billion.[5] To be able to manufacture safe food different
concepts have been used during the last decades. The
Codex Alimentarius Commission has proposed to use risk
analysis as the tool to quantify and manage food safety.[3]
The different components of risk analysis according to
Codex Alimentarius are shown in Fig. 1. Although the
above components must be kept distinct, exchange
of information, indicated by the intersecting circles of
Fig. 1, is essential (a good discussion of the framework of
risk assessment as well as various aspects of quantitative
risk assessment can be found at https://www.who.int/
foodsafety).