Death from diabetes is a clinical problem of cardiovascular dysfunction. “Primary cardiomyopathy” has become a loosely used in clinical circles to describe cardiac dysfunction under a wide variety of circumstances. Cardiac dysfunction during diabetes mellitus exhibits some features of all of the three categories of cardiomyopathy. Many investigators have devoted much time and energy in order to understand the reasons for the increased incidence of myocardial infarction in diabetics and the poor survival of the patients. The insulin status of patients may also represent a factor in determining the incidence of myocardial infarction. Perhaps one of the most important factors suggested to be responsible for the high mortality rate of diabetic patients who suffer a myocardial infarction is the phenomenon of the “silent” heart attack. The elevated mortality rate in diabetics is primarily due to lesions of the cardiovascular system. Hypertrophic cardiomyopathy is characterized by severe chamber hypertrophy of asymmetric nature.