ABSTRACT
The organochlorine pesticides (OCP) represent a group of pesticides with a wide variety of chemical and physical properties for individual compounds. Their common characteristics are that almost all are solid compounds and they are stable to air, light, heat, and carbon dioxide. To evaluate the hazard of the accumulated OCP quantities in tissues of the general population, the comparisons are often made with the OCP content in the tissues of exposed workers. OCPs are cumulative substances, and chronic intoxications are more common than acute ones during their application and production. The nervous system is among the target organs for OCPs. Polyneuritis, encephalopolyneuritis and astenovegetative syndromes have been reported after occupational exposure to OCPs. E. Krasnyuk found more frequent hepatitis and hepatocholecystitis in subjects working with OCPs, while Paramonchik predominantly found functional liver disturbances. Morgan et al. studied the liver functions of workers with high OCP tissue levels.
