ABSTRACT

The complexity of epigenetic regulation and the challenge of integrating epigenetics into risk assessment is just beginning to be appreciated. Epigenetic risk assessment methods are being used to a greater extent in personalized medicine. Cancer and endocrine disruption were considered as reasons for applying adjustment/extrapolation factors. The innermost region of the hair follicle is called the bulb and is in direct contact with the blood in the capillaries of the skin. The process for hair collection and testing includes cutting a lock of hair, preferably from the posterior vertex region of the scalp, and analyzing a length of 1.5 inches closest to the scalp. The cause has been opined to rest on implicit belief in the superiority of humans to other life forms. Analyzing climate-associated risks will likely require multiple independent sources of data and extrapolation based on a range of scenarios.