ABSTRACT
In the following, a conventional solid-phase synthetic strategy using polystyrene beads cross-linked with 1% divinylbenzene was going to be built. Although chloromethyl polystyrene (bought from FLUKA) was used in a few model experiments, usually we functionalized the polystyrene support by a SEAr reaction to provide loading sufficiently high for preparative purposes. Thus, approximately every second or third ring of the polystyrene had a linker (the loading was 48.5% ring substitution for our chloromethyl polystyrene while 31.3% ring substitution for the polystyrene with the phenol ether linker, according to the elemental analysis results; such polymers were not sold by any company).
