ABSTRACT

Diagnosing asthma and its subsequent phenotyping as well as endotyping require a range of techniques in both routine and research settings. Asthma was originally described as a symptom-driven disease, and decades ago, the diagnosis was primarily related to those symptoms. However, currently, a diagnosis of asthma is a unifying description of several pathophysiological mechanisms reflecting the potential complexity of the disease in an individual. No single test can objectively document the presence of asthma. Current asthma management requires documentation of the pathophysiology, phenotype and different endotypes, with a particular emphasis on those that are treatable (treatable traits). Tests that may help are described below.