ABSTRACT

The typical biomolecular motor is a protein that uses free energy from ATP (Adenosine Tri-phosphate) or other nucleotide triphosphate (NTP) hydrolysis as its fuel to produce mechanical force. The comprehension of the biomolecular motors’ role in vivo stimulates the experimental study of hybrid systems, where bio-inspired functions that include membrane transporters, rotary, nucleic acid and cytoskeletal motors, rely on the nanoscale generation of machine-driven commands. As a resolution, scientists have investigated bioinspired and biomimetic approaches and engineered mechanisms for nano-robot locomotion by mimicking the bacteria-motile structure or by using biological motors which can convert chemical energy to linear or rotation motion. Through selected examples, Chapter 7 presents a guide on molecular motors’ construction and their application in nanomedicine. It also shows us the challenge of bringing this technology to the market and its rational use.