ABSTRACT
EcoScale is a semi-quantitative tool suitable for introductory undergraduate education on green chemistry that is used to assess environmental and hazard impacts of chemicals used in a chemical reaction. In the original Edwards–Lawrence algorithm, an inherent safety index is determined. It is calculated based on an arbitrary penalty point scoring system with no mass weighting of scores and a limited number of parameters. GreenStar is a more advanced point-based system to ascertain the degree of greenness of a chemical process as compared to the EcoScale because it attempts to include all principles of green chemistry in a semiquantitative manner. Environmental assessment tool for organic synthesis is a program first made available in 2001 and is the pioneering work on automated material efficiency green metrics calculations for individual reactions and synthesis plans.
