ABSTRACT
This chapter focuses on the monodisperse spray drying technique. It is difficult to draw definitive conclusions from spray drying trials obtained using the conventional laboratory- or pilot-scale spray dryers at university or in companies, especially when the intention behind these studies was for scaling-up purposes and to optimize industrial operations. The small-scale dryers commercially available for laboratories can usually only produce very small particles, which come in all sizes and are of different morphologies, even from the same experimental run. It is usually not practical to carry out research on industrial- scale dryers, which are of the capacities of several to tens of tonnes of powder produced per hour. In fact, the complexities encountered in the small laboratory dryers and the large industrial ones are similar, so the intention of the monodisperse spray drying technique was to simplify the real situation to apply in a small laboratory. This spray drying technique is now commercially available and some recent case studies will be discussed.
