ABSTRACT

Acidosis has two types of 1° cause, each being compensated by the other system:

Respiratory: PaCO2 ↑, due to ventilation ↓

→ renal compensation, via HCO3 resorption, and acid and NH4 + excretion

Metabolic: HCO3 ↓ due to acid gain (high anion gap) or HCO3 loss (low anion gap)

→respiratory compensation, by PaCO2

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