ABSTRACT

Nanomedicine is the design and development of therapeutics and diagnostic tools, distinguished by the nanoscopic scale of its delivery vehicles and diagnostic agents. Polymeric materials have also played a crucial role in the research and development of nanomedicines. Ligand-receptor interaction can be utilized to concentrate the nanomedicine at the diseased tissue in-vivo, producing a preferred distribution profile. Conventional polymeric nanomedicines utilize polymers as delivery vehicles to modify the drugs’ biodistribution and enhance their efficacy. Advances in nanomedicine arise through the improvement of novel nanocarriers and technology for drug delivery. Ethical matters have been raised by bioethical researchers who believe that nanomedicine could be manipulated to harm the human body rather than healing it, besides their uses for terrorism purposes. In the human body, nanosized particulates behave very differently from larger particles. Iron oxides occur naturally in the human heart, spleen, and liver, which indicate their biocompatibility and non-toxicity at a physiological concentration.