This chapter develops an understanding of the distinct impact the changing air pollution levels have on the resulting ozone profiles in these two atmospheric layers such as troposphere and stratosphere. The chemical pathways for the formation and removal of gaseous pollutants in the troposphere are controlled largely by atoms and free radicals, despite the fact that they are present at low concentrations. The chapter explores some harmful impacts of stratospheric ozone depletion on ultraviolet (UV) radiation and the state of art of the protective measures to reduce exposure. Ozone can be formed from oxidation of methane and/or carbon monoxide, in the presence of nitrogen oxide catalysts. If all stratospheric ozone could be brought down to sea level and spread evenly around the globe, the pressure of the atmosphere it would squeeze it into a layer of 3 mm thickness. Ozone depletion potential is considered one of the key indicators in environmental impact assessment.