ABSTRACT
Compiled by C. C. Bigelow and M. Channon.
Assumed values.
REFERENCES
. Tanford, / . Am. Chem. Soc., 184, 4240 (1962).
. Nozaki and T anford ,/. Biol. Chem., 246,2211 (1971).
a
Average Protein hydrophobicity Reference
1 Acetoacetic acid decarboxylase (Clostridium acetobutylicum)
1,140
2 Acetylcholine receptor (Electrophorus electricus)
1,060
3 Acetylcholinesterase (Electrophorus electricus)
4 A-Acetyl-/3-D-glucosaminidase (Aspergillus oryzae)
1,050
5 V-Acetyl-/3-D-glucosaminidase-A (beef spleen)
6 A-Acetyl-/3-D-glucosaminidase-B (beef spleen)
7 A-Acetyl-/3-D-glucosaminidase-A (porcine kidney)
1,040
8 A-Acetyl-j3-D-glucosaminidase-B (porcine kidney)
1,030
9 A-Acetyl-p-D-glucosaminidase (human plasma)
10 Ace tylornithine 7 -transaminase (Escherichia coli)
11 O-Acetylserine sulfhydrylase A (Salmonella typhimurium)
12 a ! -Acid glycoprotein (human plasma)
1,040
13 Actin (Acanthamoeba castellani)
1,030
14 Actin (beef carotid)
15 Actin (beef heart muscle)
Average Protein hydrophobicity
16 Actin (beef skeletal muscle)
Reference
17 Actin (brown trout)
1,000
18 Actin (chicken)
1,010
19 Actin (fish)
20 Actin (frog)
21 Actin (human platelet)
22 Actin (human uterus)
23 Actin (lamb)
24 Actin (mollusc)
25 Actin (Pig)
26 Actin (rabbit muscle)
1,010
27 Actin (rabbit muscle)
28 Actin (sheep uterus)
29 Acylcarrier protein (Escherichia coli)
30 Acylphosphatase (bovine brain)
31 Acylphosphatase (horse muscle)
32 Adenosine and adenosine monophosphate deaminase {Aspergillus oryzae)
33 Adenosine deaminase (calf intestinal muscle)
1,010
34 Adenosine deaminase (calf spleen)
35 Adenosine monophosphate deaminase (rabbit muscle)
1,060
36 Adenosine monophosphate nucleosidase (Azotobacter vinelandii)
37 Adenosine triphosphatase, (Na+ + K+), large chain (canine renal medulla)
1,040
38 Adenosine triphosphatase, (Na+ + K+), small chain (canine renal medulla)
1,130
39 Adenosine triphosphate-creatine transphosphorylase (rabbit)
40 Adenylate cyclase (Brevibacterium liquefaciens)
Protein
Adenylosuccinate - AMP-lyase {Neurospora sp.)
Average hydrophobicity
Reference
42 Adrenodoxin (bovine)
43 Adrenodoxin reductase (bovine adrenal gland)
44 Aequorin (Aequorea)
45 Agglutinin (wheat germ)
46 Alanine amino transferase (rat liver)
47 Albumin (bovine plasma)
48 Albumin (dog plasma)
49 Albumin (human serum)
50 Albumin (rat serum)
51 Alcohol dehydrogenase (horse liver)
1,030
52 Aldehyde dehydrogenase, protein A (Baker’s yeast)
53 Aldolase B (rabbit liver)
54 Aldolase C (rabbit brain)
55 Aldolase, fructose-1,6-diphosphate {Boa constrictor constrictors)
56 Aldolase, fructose-1,6 -diphosphate {Discostichus mawsonii)
57 Aldolase, fructose-1,6 -diphosphate (Gallus domesticus, brain)
58 Aldolase, fructose-1,6 -diphosphate {Gallus domesticus, breast muscle)
59 Aldolase, fructose-1,6 -diphosphate {Gallus domesticus, liver)
60 Aldolase, fructose diphosphate {Micrococcus aerogenes)
61 Aldolase, fructose-1,6 -diphosphate (ox)
62 Aldolase, fructose-1,6 -diphosphate (porcine)
63 Aldolase, fructose-1,6 -diphosphate (rabbit liver)
64 Aldolase, fructose-1,6 -diphosphate (rabbit muscle)
65 Aldolase, fructose-1,6 -diphosphate (sturgeon)
Protein
Aldolase, fructose-1,6 -diphosphate {Trematomus borchgrevinki)
Average hydrophobicity
Reference
67 Aldolase, fructose-1,6-diphosphate (yeast)
6 8 Aldolase, 2-keto-3-deoxy-6-phosphogluconate (Pseudomonas putida)
1,090
69 Alkaline phosphatase CBacillus licheniformis MC 14)
70 Alkaline phosphatase (Escherichia coll)
71 Alkaline proteinase-B {Streptomyces rectus proteolyticus)
72 cj-Amidase (rat liver)
73 Amino acid decarboxylase, aromatic (porcine kidney)
1,050
74 D-Amino acid oxidase (porcine kidney)
1,050
75 Aminopeptidase (Aeromonas proteolytica)
76 Aminotripeptidase, TP-2 (porcine kidney)
1,090
77 Amylase CBacillus macerans)
78 Amylase (rat pancreas)
79 Amylase PI (rabbit pancreas)
80 Amylase PII (rabbit pancreas)
81 Amylase Pill (rabbit pancreas)
82 Amylase (rabbit parotid)
83 a-Amylase (Aspergillus oryzae)
84 a-Amylase CBacillus stearothermophilus)
85 a-Amylase (Bacillus subtilis)
8 6 a-Amylase (porcine pancreas)
1,040
87 a-Amylase (human saliva)
8 8 a-Amylase-I (porcine pancreas)
89 a-Amylase-II (porcine pancreas)
90 Anthranylate synthetase, component I (Pseudomonas putida)
Protein
Anthranylate synthetase, component II (Pseudomonas putida)
Average hydrophobici ty Reference
92 Apo-high density lipoprotein (bovine plasma)
93 Apolipoprotein - alanine-I (human plasma)
94 Apolipoprotein - alanine-II (human plasma)
95 Apolipoprotein - glutamine-I (human plasma)
96 Apolipoprotein - glutamine-I (porcine plasma)
97 Apolipoprotein - glutamine-II (human plasma)
98 Apolipoprotein-valine (human plasma)
99 Apovitellinin-I CDromaeus novaehollandiae)
1 0 0 a-L-Arabinofuranosidase {Aspergillus niger K l)
103 Arginine decarboxylase {Escherichia coli)
104 Arginine kinase {Callinectus sapidus)
105 Arginine kinase {Homarus americanus)
106 Arginine kinase, negative {Limulus polyphemus)
107 Arginine kinase, neutral {Limulus polyphemus)
108 Arginine kinase {Pagurus bernhardus)
109 Asparaginase {Escherichia coli B)
113 Aspartate aminotransferase (rat brain, cytoplasm)
1,050
114 Aspartate aminotransferase (rat brain, mitochondria, fraction II)
115 Aspartate aminotransferase (rat brain, mitochondria, fraction III)
Average Protein hydrophobicity Reference
117 (Alcaligenes faecalis)
118 CPseudomonas dacunhae)
Aspartate transcarbamylase, catalytic chain 990
119 CEscherichia coli)
Aspartate transcarbamylase, regulatory chain 980
Aspartokinase, lysine sensitive 940
CEscherichia coli K-12, HfrH)
Aspergillopeptidase B 810
Avidin 930
123 (chicken egg)
Azurin 880
124 {Pseudomonas fluorescens)
Azurin 970
125 {Pseudomonas polym yxa)
Biotin carboxyl carrier protein 1,300
{Escherichia coli)
Blastokinin 1,030
127 (rabbit)
Bradykininogen 980
128 (bovine)
a-Bungarotoxin 1,040
129 {Bungarus multicintus)
130 (human plasma)
Calcitonin 1,080
(bovine)
132 (human)
133 (porcine)
Calcitonin 860
134 (salmon)
Calcium-binding protein 780
135 (bovine adrenal medulla)
Calcium-binding protein 930
(chick duodenal mucosa)
Calcium-binding protein-B (parvalbumin) 890
137 {Cyprinus carpio muscle)
Calcium-binding protein 740
138 (porcine brain)
Carbamyl phosphate synthetase 960
139 {Escherichia coli B)
140 (bovine)
Carbonic anhydrase {Gallus domesticus)
Protein
Carbonic anhydrase (parsley)
Average hydrophobicity Reference
142 Carbonic anhydrase (sheep)
143 Carbonic anhydrase B (bovine)
144 Carbonic anhydrase B (equine)
145 Carbonic anhydrase B (Macaca mulata)
146 Carbonic anhydrase B (porcine)
147 Carbonic anhydrase C (equine)
148 Carbonic anhydrase C (porcine)
1,010
149 j3-Carboxy-cis,cis-muconate lactonizing enzyme (.Pseudomonas putida)
150 7 -Carboxymuconolactone decarboxylase (Pseudomonas putida)
1,170
151 Carboxypeptidase A (bovine pancreas)
152 Carboxypeptidase A (Penaeus setiferus)
153 Carboxypeptidase B {Penaeus setiferus)
154 Carboxypeptidase B (Protopterus aethiopicus)
155 Procarboxypeptidase B {Protopterus aethiopicus)
156 Carboxypeptidase B (dogfish pancreas)
1,070
157 Carboxypeptidase Y (yeast)
1,050
158 Carboxytransphosphorylase (propionic acid bacteria)
159 Catalase (bovine liver)
160 Colchicine-binding protein (sea urchin)
161 Colchicine-binding protein (porcine brain)
162 Chorionic gonadotropin-a (human)
163 Chorionic gonadotropin-j3 (human)
1,120
164 Chorismate mutase-prephenate dehydratase {Escherichia coli K-12)
165 Chymoelastase, lysine free {Streptomyces griseus K-l)
Protein
Chymoelastase, guanidine stable {Streptomyces griseus K-l)
Average hydrophobicity
Reference
167 Chymotrypsin, anionic (fin whale)
1,060
168 Chymotrypsin II (human)
169 Chymotrypsinogen A (dogfish)
170 Chymotrypsinogen B (bovine pancreas)
171 Chymotrypsinogen B (porcine pancreas)
172 Chymotrypsinogen C (porcine pancreas)
173 Cocoonase (Antheraea pernyi)
174 Cocoonase (Antheraea polyphemus)
175 Prococoonase (Antheraea polyphemus)
176 Colicin Ia-CA53 CEscherichia coli)
177 Colicin Ib-P9 CEscherichia coli)
178 Collagen (chicken tendon)
179 Collagen, a-fraction (calf skin)
180 Collagen, spongin B (sponge)
181 Collagen (sturgeon swim bladder)
182 Collagenase (Uca pugilator)
183 Conalbumin (chicken)
184 Corrinoid protein {Clostridium thermoaceticum)
185 Creatine kinase (Cyprinus carpio L.)
186 Creatine kinase (human)
187 Crotonase {Clostridium acetobutylicum)
188 Cro toxin {Crotalus terrificus terrificus)
189 Cystathionase (rat liver)
190 Cytochrome b s (bovine liver)
Protein
Cytochrome b 5 (equine liver)
Average hydrophobicity Reference
192 Cytochrome b 5 (porcine liver)
193 Cytochrome c (horse heart)
1,050
194 Cytochrome c (chicken)
1,050
195 Cytochrome c (cow, pig, sheep)
1,020
196 Cytochrome c (dog)
1,070
197 Cytochrome c (kangaroo)
1,130
198 Cytochrome c (king penguin)
1,060
199 Cytochrome c (Macaca mulata)
1,060
1,060
1,070
1,070
203 Cytochrome c (rattlesnake)
1,050
204 Cytochrome c (Saccharomyces)
1,040
205 Cytochrome c (tuna)
1,050
206 Cytochrome c (turkey)
1,050
207 Cytochrome CA (Humicola lanuginosa)
208 Cytochrome C 3 (Desulfovibrio desulfuricans)
209 Cytochrome C 3 CDesulfovibrio gigas)
213 Daunorubicin reductase (rat liver)
214 3-Deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase
215 Deoxycytidylate deaminase (T2 r+ bacteriophage)
Protein Average
hydrophobicity Reference
216 Deoxyribonuclease 930
217 (bovine pancreas)
Deoxyribonuclease A 970
218 (bovine pancreas)
Deoxyribonuclease B 980
219 (bovine pancreas)
Deoxyribonuclease C 980
Deoxyribonuclease II 1,050
(porcine spleen)
Deoxyribonucleic acid ligase 970
223 (calf spleen)
a-Dialkylamino transamidase 930
224 (Pseudomonas cepacia)
Dihydrofolate reductase 1,030
225 (T4 bacteriophage)
Dihydrofolate reductase 1,030
(Escherichia coli MB 1428)
227 (Lactobacillus casei)
Dihydrofolate reductase 1,060
228 (Streptococcus faecium)
3,4-Dihydroxyphenylacetate-2,3-oxygenase 980
229 (Pseudomonas ovalis)
Dopamine-0-hydroxylase 950
230 (bovine adrenal)
Elastin 940
(bovine aorta)
Elastin 990
232 (bovine ear cartilage)
Elastin 980
233 (bovine ligamentum nuchae)
Encephalitogenic A-l protein 850
234 (bovine brain)
Encephalitogenic A-l protein 820
235 (human brain)
Endopolygalac tu ronase 850
(Verticillium albo-atrum)
Enolase 970
237 (monkey muscle)
Enolase 980
238 (Onkorhynchus beta)
Enolase 930
239 (Onkorhynchus kisutch)
Enolase 990
240 (rabbit muscle)
Enolase 900 (Thermits X-l)
Protein Average
hydrophobicity Reference
241 Enolase {Thermus aquaticus YT-1)
242 Enolase (yeast)
243 Entero toxin C 0Staphylococcus 137)
244 Entero toxin E {Staphylococcus aureus FRI-326)
245 Entero toxin A {Staphylococcus aureus 13N-2909)
246 Erythrocuprein (human)
247 Esterase (pig liver)
248 Estradiol dehydrogenase (human placenta)
249 Factor III lac {Staphylococcus aureus)
250 Factor VIII (bovine plasma)
1,030
251 Factor VIII (human plasma)
252 Ferredoxin {Chlorobium thiosulfatophilum)
253 Ferredoxin {Clostridium pasteurianium)
254 Ferredoxin {Chromatium)
255 Ferredoxin {Cyperus rotundus)
256 Ferredoxin {Desulfovibrio gigas)
257 Ferredoxin (iSpinacea)
258 Ferredoxin {Scenedesmus)
259 Ferredoxin I {Azotobacter vinelandii)
1,050
260 Ferredoxin I {Bacillus polymxa)
261 Ferredoxin II {Bacillus polymxa)
262 Ferritin (horse spleen)
263 Ferritin (tadpole red blood cell)
264 Fibrinogen B (lobster)
265 Fibroin {Bombyx mori)
Protein Average
hydrophobicity Reference
266 Fibroin (Tussah)
267 Ficin II (Ficus glabrata)
268 Ficin III (Ficus glabrata)
269 Flagellin (Proteus vulgaris)
270 Flagellin (Salmonella SJ 25)
271 Flagellin (Salmonella typhimurium)
272 Flavodoxin (Qostridium MP)
273 Flavodoxin (Clostridiam pasteurianiu m )
274 Flavodoxin (Desulfovibrio gigas)
275 Flavodoxin (Desulfovibrio vulgaris)
276 Flavodoxin (Peptostreptococcus elsdenii)
277 Follicle stimulating hormone (ovine)
278 A-formimino-L-glutamate iminohydrolase (Pseudomonas ATCC 11299b)
279 Fructose-1,6 -diphosphatase (porcine kidney)
280 0 -Galactosidase (Escherichia coli)
281 Gastricin (human)
282 Gastricin (porcine)
283 Gliadin SP 2-2 (Cappelle 1966 flour)
1,300
284 Gliadin SP 2-1 (wheat, Wichita 1963)
1,250
285 Gliadin SP 2-2 (wheat, Wichita 1963)
1,180
286 Gliadin SP 2-3 (wheat, Wichita 1963)
1,180
287 Globulin, 0.6 S y 2 (human plasma)
1,090
288 Glucagon (bovine)
289 Glutamate decarboxylase (Escherichia coli)
1,080
290 Glutamate dehydrogenase (bovine liver)
Protein
Glutamate dehydrogenase (Neurospora crassa)
Average hydrophobicity Reference
292 Glutaminase-asparaginase CAchromobacteraceae)
293 Glutamine synthetase (rat liver)
294 7 -Glutamyl cyclo transferase (porcine liver)
295 Glyceraldehyde-3-phosphate dehydrogenase CBacillus stearothermophilus)
296 Glyceraldehyde-3-phosphate dehydrogenase (bovine liver)
297 Glycerol-3-phosphate dehydrogenase (rabbit muscle)
1,040
298 Glycocyamine kinase (Nepthys coeca)
299 Glycogen phosphorylase (Baker’s yeast)
1,050
300 Glycogen phosphorylase {Carcharhinus falciformis)
1,080
301 Glycogen phosphorylase (human)
1,060
302 Glycogen phosphorylase (rabbit liver)
1,060
303 Glycogen phosphorylase (rat)
1,070
304 Glycogen synthetase (porcine kidney)
305 7 -Glycoprotein (human plasma)
1,070
306 Growth hormone (human)
307 Haptoglobin, a 2-chain (human plasma)
308 Haptoglobin, c^g-chain (human plasma)
309 Haptoglobin, /J-chain (human plasma)
1,020
310 Hemagglutinin CLens esculenta Muench)
1,000
311 Hemagglutinin I (Pisum sativum L. var. pyram)
312 Hemagglutinin 11 (Pisum sativum L. var. pyram )
313 Hemagglutinin (Robina pseudoaccacia)
314 Hemagglutinin 11 (snail)
1,070
315 Hemagglutinin (soy)
Protein Average
hydrophobicity Reference
316 Hemagglutinin 950
317 (Ulex europeus)
Hemerythrin 1,170
318 {Golfingia gouldii)
319 (Cancer magister)
Hemocyanin 980
320 (Crustaceae C. sapidus)
Hemocyanin 980
{Crustaceae E. spinifrons)
Hemocyanin 980
322 {Crustaceae H. vulgaris)
Hemocyanin 980
323 {Crustaceae P. vulgaris)
Hemocyanin 1,050
324 {Mollusca E. moschata)
325 {Mollusca M. brandaris)
{Mollusca M. tranculus)
Hemocyanin 1,050
327 {Mollusca 0 . macropus)
Hemocyanin 1,080
328 {Mollusca O. vulgaris)
Hemocyanin 980
329 {Xiphosura L . polyphemus)
Hemoglobin 980
330 {Ascaris body wall)
{Entosphenus japonicus)
Hemoglobin 870
332 {Glycera dibranchiata)
333 {Catostomus clarkii)
Hemoglobin, a-chain 960
334 (human)
Hemoglobin, 7 -chain 960
335 (bovine)
Hemoglobin, 7 -chain 960
(human)
Hemoglobin, F-l 1,170
337 {Eptatretus burgeri)
Hemoglobin, F-2 1,160
338 {Eptatretus burgeri)
Hemoglobin, F-3 1,140
339 {Eptatretus burgeri)
Hemoglobin, F-4 1,040
340 {Eptatretus burgeri)
Protein
Hemopexin (rabbit)
Average hydrophobicity
Reference
342 High potential iron sulfur protein (Chromatium vinosum D)
343 High potential iron sulfur protein (Thiocapsa pfennigii)
344 Histidine: ammonia lyase (Pseudomonas ATCC 11299b)
345 Histidine-binding protein 0 Salmonella typhimurium)
346 Histidine decarboxylase CLactobacillus 30a)
347 L-Histidinol phosphate aminotransferase 0 Salmonella typhimurium )
348 Histidyl-tRNA synthetase 0 Salmonella typhimurium)
349 Histone III (calf thymus)
350 Histone III (Letiobus bubalus)
351 Histone III (pea)
352 Histone III (rainbow trout)
353 Hyaluronidase (bovine testicular)
1,030
354 Hydrogenase (<Clostridium pasteurianium W5)
1,160
355 3-Hydroxyacyl coenzyme A dehydrogenase (porcine heart muscle)
356 0 -Hydroxybutyrate dehydrogenase (bovine heart mitochondria)
357 a 1 -Hydroxysteroid dehydrogenase CPseudomonas testosteroni)
358 17-0-Hydroxysteroid dehydrogenase (human placenta)
359 Immunoglobulin, Eu heavy chain (human plasma)
360 Immunoglobulin, Eu light chain (human plasma)
361 Immunoglobulin, New \-chain (human plasma)
362 Inorganic pyrophosphatase (yeast)
1,130
363 Insulin (bovine)
364 Insulin (cod)
365 Invertase {Saccharomyces FH4C)
Protein Average
hydrophobicity Reference
366 Isoamylase I (porcine pancreas)
367 Isoamylase II (porcine pancreas)
368 Isocitrate dehydrogenase (Azotobacter vinelandii ATCC 9104)
369 Isocitrate dehydrogenase (porcine liver)
370 Isomerase I (rabbit)
1,080
371 Isomerase II (rabbit)
372 Keratinase (Trichophyton mentagrophytes)
373 A5 -3-Ketosteroid isomerase CPseudomonas testosteronii)
374 a-Lactalbumin (bovine milk)
1,050
375 Lactoferrin (bovine)
376 /3-Lactoglobulin (caprid)
1,040
377 /3-Lactoglobulin A (bovine)
1,070
378 /3-Lactoglobulin A (ovine)
1,050
379 /3-Lactoglobulin B (bovine)
1,060
380 /3-Lactoglobulin B (ovine)
1,050
381 /3-Lactoglobulin C (bovine)
1,070
382 Lactoperoxidase (bovine milk)
1,080
383 Lectin, a-D-galactosy 1-binding (Bandeiraea simplicifola)
384 Leghemoglobin I (soy bean root nodule)
385 Leghemoglobin II (soy bean root nodule)
386 Leucine aminopeptidase (bovine lens)
387 Lipase (rat pancreas)
388 /3-Lipolytic hormone (porcine pituitary)
389 7 -Lipolytic hormone (sheep)
390 a-Lipovitellin (chicken egg yolk)
Protein
Luciferase (Renilla reniformis)
Average hydrophobicity
Reference
392 Luciferase-a (MAV)
393 Luciferase-0 (MAV)
394 Luciferase-a CPhotobacterium flscheri)
395 Luciferase-/3 CPhotobacterium flscheri)
396 Luteinizing hormone-a chain (equine)
1,070
397 Luteinizing hormone - 0 chain (equine)
398 Lysine decarboxylase CEscherichia coli)
1,080
399 L-Lysine monooxygenase (Pseudomonas fluorescens)
1,040
400 Lysostaphin {Staphylococcus aureus)
401 Lysozyme (Chalaropsis)
402 Lysozyme, chick type (black swan)
403 Lysozyme, goose type (black swan)
404 Lysozyme (chicken)
405 Lysozyme (papaya)
1,080
406 Lysozyme (turkey)
407 Lysyl: tRNA ligase {Escherichia coli)
408 Lysyl: tRNA ligase (yeast)
1,040
409 a-Lytic protease {Sorangium sp.)
410 0 -Lytic protease {Sorangium sp.)
411 Malate dehydrogenase {Bacillus subtilis)
412 Malate-lactate transhydrogenase {Micrococcus lactilyticus)
413 Malate-vitamin k reductase {Mycobacterium phleii)
414 L-Malic enzyme (Escherichia coli)
415 0 -Melanocyte stimulating hormone (bovine)
1,180
Protein Average
hydrophobicity Reference
416 Melilotate hydroxylase 970
417 CPseudomonas sp.)
Methionyl-tRNA synthetase 1,040
418 CEscherichia coli)
/3-Methyl aspartase 980
419 {Clostridium tetanomorphum)
0 -Methylcrotonylcoenzyme A carboxylase 890
420 {A chromobacter)
Methylmalonatesemialdehydedehydrogenase 1,030
{Pseudomonas aeruginosa)
Molydbenum-iron protein 1,010
422 (soy bean root nodule bacteroid)
Monellin 1,140
423 {Dioscoreophyllum cumminsii)
Motilin 1,020
424 (porcine intestinal mucosa)
cis,cis-Muconate lactonizing enzyme 990
425 {Pseudomonas putida)
Muconolactone isomerase 1,070
{Pseudomonas putida)
Mutarotase 850
427 (bovine kidney cortex)
Myoglobin 1,000
428 (human)
Myoglobin 1,040
429 (whale)
Myoglobin 1,030
430 {Zalophus califomianus)
Myohemerythrin 1,090
{Dendrostamum pyroides)
Myosin 880
432 (bovine heart)
Myosin 860
433 (cod)
Myosin 890
434 (rabbit)
Myosin 880
435 (tuna)
Neocarzinostatin 750
{Streptomyces carzinostaticus F-41)
Neurophysin I 850
437 (bovine pituitary)
Neurophysin II 830
438 (bovine pituitary)
Neurophysin III 820
439 (bovine pituitary)
Neurotoxin I 1,070
440 {Androctonus australis)
Neurotoxin II {Androctonus australis)
Protein
Neurotoxin III (Androctonus australis)
Average hydrophobicity
Reference
442 Neurotoxin I {Leiurus quinquestriatus quinquestriatus)
1,040
443 Neurotoxin II CLeiurus quinquestriatus quinquestriatus)
444 Neurotoxin III (.Leiurus quinquestriatus quinquestriatus)
1,030
445 Neuro toxin IV CLeiurus quinquestriatus quinquestriatus)
1,050
446 Neurotoxin V CLeiurus quinquestriatus quinquestriatus)
447 Nuclease CMicrococcus sodonencis ATCC 11880)
448 Nuclease {Staphylococcus)
449 Nucleoside diphosphokinase (Brewer’s yeast)
1,030
450 Nucleoside phosphotransferase-A-chain (carrot)
451 Nucleoside phosphotransferase-B-chain (carrot)
452 5'-Nucleotidase {Escherichia coli)
453 Ornithine transcarbamylase (bovine liver)
1,040
454 Ornithine transcarbamylase {Streptococcus faecalis)
455 Ovalbumin (chicken egg)
456 Ovomacroglobulin (chicken egg)
1,040
457 Ovomucin (chicken egg)
458 Ovomucoid (chicken egg)
459 Ovotransferrin (chicken egg)
460 2-Oxoglutarate dehydrogenase (porcine heart)
461 Oxytocin (mammalian)
1,290
462 Papain (papaya)
1,030
463 Parathyroid hormone (bovine)
464 Parvalbumin (rabbit skeletal muscle)
465 Penicillocarboxypeptidase-S {Penicillium janthinellum)
Protein Average
hydrophobicity Reference
466 Pepsin 940
467 (bovine)
Pepsin 930
468 (human)
Pepsin I 910
469 (Rhizopus chinertsis)
Pepsin II 910
470 CRhizopus chinensis)
Pepsinogen A 960
(bovine)
Pepsinogen A 920
A ll (Mustelus cams)
Pepsinogen A 970
473 (porcine)
474 (porcine)
Phenylalanine ammonia lyase 1,030
475 {Solarium tuberosum)
Phenylalanine ammonia lyase 940
{Zea mays L.)
Phenylalanine hydroxylase 930
A ll (rat liver)
Phosphatidyl serine decarboxylase 1,050
478 {Escherichia coli)
Phosphoenol pyruvate carboxykinase 1,030
479 (yeast)
Phosphofructokinase 940
480 (chicken liver)
(rabbit muscle)
482 (human)
483 (rabbit muscle)
Phosphoglycerate kinase 980
484 (human erythrocyte)
Phospholipase A 910
485 {Bitis gabonica venom)
Phospholipase At 1,030
{Crotalus adamanteus)
Phospholipase A2 920
487 {Crotalus atrox)
Phospholipase A 950
488 {Laticuda semifasciata)
Phosphorylase 1,070
489 (frog skeletal muscle)
Phycocyanin 910
490 CP. calothricoides)
Phycocyanin {S. lividicus)
1,040
Protein Average
hydrophobicity Reference
491 Phycoerythrin 830
492 {P. tenera)
493 (oat)
Plastocyanin 880
494 (parsley)
Prealbumin 990
495 (human serum)
Prealbumin, Pt 1-1 990
(monkey)
497 (monkey)
498 (bovine)
499 (Squalus acanthias)
Progesterone-binding protein 1,040
500 (guinea pig plasma)
Prohistidine decarboxylase 990
(Lactobacillus 30a)
Prolactin 950
502 (ovine pituitary)
Protease 940
503 (.Bacillus thermoprotolyticus)
Protease 940
504 {Mucor miehei CBS 370.65)
Protease 900
505 {Staphylococcus aureus V 8 )
Protease - 700
(Streptomyces griseus)
Protease-acid 950
507 {Rhizopus chinensis)
Protein kinase modulator 720
508 (lobster tail muscle)
Prothrombin 960
509 (bovine)
510 (Rana pipiens pipiens)
Putidaredoxin 910
{Pseudomonas putida)
Putrescine oxidase 860
512 {Micrococcus rubens)
513 (bovine skeletal muscle)
Quinonoid dihydropterin reductase 890
514 (sheep liver)
Retinol-binding protein 960
515 (human)
Retinol-binding protein (monkey)
Protein Average
hydrophobicity Reference
516 Rhodopsin (bovine)
517 Riboflavin-binding protein (chicken)
518 Ribonuclease CAspergillus fumigatus)
519 Ribonuclease CBacillus subtilis)
520 Ribonuclease (bovine pancreas)
521 Rubonuclease (ovine pancreas)
522 Ribonuclease Ch. {Chalaropsis sp.)
523 Ribonuclease N (Neurospora crassa)
524 Ribonuclease Rt (Rhizopus oligosporus)
525 Ribonuclease R 2 CRhizopus oligosporus)
526 Ribonuclease Tj CAspergillus oryzae)
527 Ribonuclease Uj (UstUago sphaerogerta)
528 Ribonucleotide reductase (Lactobacillus leichmanii)
529 Ribulose diphosphate carboxylase (,Hydrogenomonas eutropha)
530 Ribulose diphosphate carboxylase CHydrogenomonas facilis)
531 Ribulose diphosphate carboxylase (Rhodospirillum rubrum)
532 Rubredoxin {Clostridium pasteurianum)
533 Rubredoxin {Micrococcus aerogenes)
534 Rubredoxin {Pseudomonas oleovorans)
535 D-Serine dehydratase {Escherichia coli)
536 Streptokinase (human plasma)
537 Subtilisin BPN {Bacillus subtilis)
538 Succinyl coenzyme A synthetase {Escherichia coli)
539 Sucrose synthetase {Phaseolus aureus)
1,040
540 Superoxide dismutase {Neurospora crassa)
Protein Average
hydrophobicity Reference
541 Thermolysin CBacillus thermoproteolyticus)
542 Thioredoxin (T-4 bacteriophage)
1,150
543 Thioredoxin II (yeast)
544 Thrombin (bovine)
1,040
545 Thymidylate synthetase (T-2 bacteriophage)
1,140
546 Thyroglobulin (calf)
547 Thyroglobulin (human)
548 Thyroglobulin (porcine)
549 Thyroglobulin (rabbit)
550 Thyroglobulin (sheep)
551 Thyroid stimulating hormone - a-chain (human)
552 Thyroid stimulating hormone - /3-chain (human)
1,170
553 Toxin FVII (Dendroaspis angusticeps)
554 Toxin o l (Dendroaspis polylepsis)
555 Toxin y (.Dendroaspis polylepsis)
556 Toxin 4 {Enhydrina schistosa)
557 Toxin 5 CEnhydrina schistosa)
558 Toxin (Laticauda colubrina)
559 Toxin (Laticauda laticauda)
560 Toxin a (Laticauda semifasciata)
561 Toxin b (Laticauda semifasciata)
562 Toxin {Naja haje haje)
563 Toxin b {Naja melanoleuca)
1,090
564 Toxin d {Naja melanoleuca)
565 Toxin {Naja naja atra)
Protein
Toxin (Naja nigricollis)
Average hydrophobicity
Reference
567 o-Toxin A {Staphylococcus aureus Woods 46)
568 a-Toxin B {Staphylococcus aureus Woods 46)
569 Transaminase B {Salmonella typhimurium)
570 Transcortin (guinea pig)
571 Transcortin (human)
572 Transcortin (rabbit)
573 Transcortin (rat)
1,030
574 Transferrin (bovine)
575 Transferrin (equine)
576 Transferrin (human)
577 Transferrin (porcine serum)
578 Transferrin (rabbit serum)
579 Triose phosphate dehydrogenase {Bom bus nevadensis)
1,040
580 Triose phosphate dehydrogenase (honey bee)
581 Triose phosphate dehydrogenase (lobster)
582 Triose phosphate dehydrogenase (porcine)
583 Triose phosphate isomerase-I (human erythrocyte)
584 Triose phosphate isomerase-III (human erythrocyte)
585 Triose phosphate isomerase (rabbit muscle)
586 Triose phosphate isomerase (yeast)
587 Troponin-C (rabbit muscle)
588 Troponin-T (rabbit muscle)
1,040
589 Trypsin {Evasterias trochelli)
590 Trypsin (lungfish)
Protein
Trypsin (human)
Average hydrophobicity
Reference
592 Trypsin, anionic (human)
593 Trypsin (porcine)
594 Trypsin (sheep)
595 Trypsin (shrimp)
596 Trypsin (iStreptomyces griseus)
597 Trypsin inhibitor (Ascaris lumbricoides suis)
598 Trypsin inhibitor (bovine pancreas)
1,150
599 Trypsin inhibitor (porcine pancreas)
600 Trypsin inhibitor (bovine pancreas)
1,070
601 Trypsin inhibitor I (Phaseolus vulgaris)
602 Trypsin inhibitor II CPhaseolus vulgaris)
603 Trypsinogen (bovine)
604 Trypsinogen (dogfish)
605 Trypsinogen (lungfish)
606 Trypsinogen, anionic (porcine)
607 Trypsinogen (sheep)
608 Tryptophan synthetase A CEscherichia coli)
1,060
609 Tryptophan synthetase-a-chain (Aerobacter aerogenes)
1,060
610 Tryptophan synthetase - a-chain CBacillus subtilis)
611 Tryptophan synthetase - a-chain CSalmonella typhimurium )
612 Tryptophan synthetase - /3-chain CBacillus subtilis)
613 Tryptophanase (Bacillus alvei)
614 Tryptophanase (.Escherichia coli B/lt7-A)
1,030
615 Tyrosyl-tRNA synthetase (Bacillus stearothermophilus)
1,060
Protein Average
hydrophobicity Reference
616 Urease (jackbean meal)
617 Urokinase S-l (human urine)
1,030
618 Urokinase S-2 (human urine)
619 Valine :tRNA ligase (yeast)
1,080
620 Vasopressin, lysine (mammalian)
Compiled by C. C. Bigelow and M. Channon.