ABSTRACT

Compiled by C. C. Bigelow and M. Channon.

Assumed values.

REFERENCES

. Tanford, / . Am. Chem. Soc., 184, 4240 (1962).

. Nozaki and T anford ,/. Biol. Chem., 246,2211 (1971).

a

Average Protein hydrophobicity Reference

1 Acetoacetic acid decarboxylase (Clostridium acetobutylicum)

1,140

2 Acetylcholine receptor (Electrophorus electricus)

1,060

3 Acetylcholinesterase (Electrophorus electricus)

4 A-Acetyl-/3-D-glucosaminidase (Aspergillus oryzae)

1,050

5 V-Acetyl-/3-D-glucosaminidase-A (beef spleen)

6 A-Acetyl-/3-D-glucosaminidase-B (beef spleen)

7 A-Acetyl-/3-D-glucosaminidase-A (porcine kidney)

1,040

8 A-Acetyl-j3-D-glucosaminidase-B (porcine kidney)

1,030

9 A-Acetyl-p-D-glucosaminidase (human plasma)

10 Ace tylornithine 7 -transaminase (Escherichia coli)

11 O-Acetylserine sulfhydrylase A (Salmonella typhimurium)

12 a ! -Acid glycoprotein (human plasma)

1,040

13 Actin (Acanthamoeba castellani)

1,030

14 Actin (beef carotid)

15 Actin (beef heart muscle)

Average Protein hydrophobicity

16 Actin (beef skeletal muscle)

Reference

17 Actin (brown trout)

1,000

18 Actin (chicken)

1,010

19 Actin (fish)

20 Actin (frog)

21 Actin (human platelet)

22 Actin (human uterus)

23 Actin (lamb)

24 Actin (mollusc)

25 Actin (Pig)

26 Actin (rabbit muscle)

1,010

27 Actin (rabbit muscle)

28 Actin (sheep uterus)

29 Acylcarrier protein (Escherichia coli)

30 Acylphosphatase (bovine brain)

31 Acylphosphatase (horse muscle)

32 Adenosine and adenosine monophosphate deaminase {Aspergillus oryzae)

33 Adenosine deaminase (calf intestinal muscle)

1,010

34 Adenosine deaminase (calf spleen)

35 Adenosine monophosphate deaminase (rabbit muscle)

1,060

36 Adenosine monophosphate nucleosidase (Azotobacter vinelandii)

37 Adenosine triphosphatase, (Na+ + K+), large chain (canine renal medulla)

1,040

38 Adenosine triphosphatase, (Na+ + K+), small chain (canine renal medulla)

1,130

39 Adenosine triphosphate-creatine transphosphorylase (rabbit)

40 Adenylate cyclase (Brevibacterium liquefaciens)

Protein

Adenylosuccinate - AMP-lyase {Neurospora sp.)

Average hydrophobicity

Reference

42 Adrenodoxin (bovine)

43 Adrenodoxin reductase (bovine adrenal gland)

44 Aequorin (Aequorea)

45 Agglutinin (wheat germ)

46 Alanine amino transferase (rat liver)

47 Albumin (bovine plasma)

48 Albumin (dog plasma)

49 Albumin (human serum)

50 Albumin (rat serum)

51 Alcohol dehydrogenase (horse liver)

1,030

52 Aldehyde dehydrogenase, protein A (Baker’s yeast)

53 Aldolase B (rabbit liver)

54 Aldolase C (rabbit brain)

55 Aldolase, fructose-1,6-diphosphate {Boa constrictor constrictors)

56 Aldolase, fructose-1,6 -diphosphate {Discostichus mawsonii)

57 Aldolase, fructose-1,6 -diphosphate (Gallus domesticus, brain)

58 Aldolase, fructose-1,6 -diphosphate {Gallus domesticus, breast muscle)

59 Aldolase, fructose-1,6 -diphosphate {Gallus domesticus, liver)

60 Aldolase, fructose diphosphate {Micrococcus aerogenes)

61 Aldolase, fructose-1,6 -diphosphate (ox)

62 Aldolase, fructose-1,6 -diphosphate (porcine)

63 Aldolase, fructose-1,6 -diphosphate (rabbit liver)

64 Aldolase, fructose-1,6 -diphosphate (rabbit muscle)

65 Aldolase, fructose-1,6 -diphosphate (sturgeon)

Protein

Aldolase, fructose-1,6 -diphosphate {Trematomus borchgrevinki)

Average hydrophobicity

Reference

67 Aldolase, fructose-1,6-diphosphate (yeast)

6 8 Aldolase, 2-keto-3-deoxy-6-phosphogluconate (Pseudomonas putida)

1,090

69 Alkaline phosphatase CBacillus licheniformis MC 14)

70 Alkaline phosphatase (Escherichia coll)

71 Alkaline proteinase-B {Streptomyces rectus proteolyticus)

72 cj-Amidase (rat liver)

73 Amino acid decarboxylase, aromatic (porcine kidney)

1,050

74 D-Amino acid oxidase (porcine kidney)

1,050

75 Aminopeptidase (Aeromonas proteolytica)

76 Aminotripeptidase, TP-2 (porcine kidney)

1,090

77 Amylase CBacillus macerans)

78 Amylase (rat pancreas)

79 Amylase PI (rabbit pancreas)

80 Amylase PII (rabbit pancreas)

81 Amylase Pill (rabbit pancreas)

82 Amylase (rabbit parotid)

83 a-Amylase (Aspergillus oryzae)

84 a-Amylase CBacillus stearothermophilus)

85 a-Amylase (Bacillus subtilis)

8 6 a-Amylase (porcine pancreas)

1,040

87 a-Amylase (human saliva)

8 8 a-Amylase-I (porcine pancreas)

89 a-Amylase-II (porcine pancreas)

90 Anthranylate synthetase, component I (Pseudomonas putida)

Protein

Anthranylate synthetase, component II (Pseudomonas putida)

Average hydrophobici ty Reference

92 Apo-high density lipoprotein (bovine plasma)

93 Apolipoprotein - alanine-I (human plasma)

94 Apolipoprotein - alanine-II (human plasma)

95 Apolipoprotein - glutamine-I (human plasma)

96 Apolipoprotein - glutamine-I (porcine plasma)

97 Apolipoprotein - glutamine-II (human plasma)

98 Apolipoprotein-valine (human plasma)

99 Apovitellinin-I CDromaeus novaehollandiae)

1 0 0 a-L-Arabinofuranosidase {Aspergillus niger K l)

103 Arginine decarboxylase {Escherichia coli)

104 Arginine kinase {Callinectus sapidus)

105 Arginine kinase {Homarus americanus)

106 Arginine kinase, negative {Limulus polyphemus)

107 Arginine kinase, neutral {Limulus polyphemus)

108 Arginine kinase {Pagurus bernhardus)

109 Asparaginase {Escherichia coli B)

113 Aspartate aminotransferase (rat brain, cytoplasm)

1,050

114 Aspartate aminotransferase (rat brain, mitochondria, fraction II)

115 Aspartate aminotransferase (rat brain, mitochondria, fraction III)

Average Protein hydrophobicity Reference

117 (Alcaligenes faecalis)

118 CPseudomonas dacunhae)

Aspartate transcarbamylase, catalytic chain 990

119 CEscherichia coli)

Aspartate transcarbamylase, regulatory chain 980

Aspartokinase, lysine sensitive 940

CEscherichia coli K-12, HfrH)

Aspergillopeptidase B 810

Avidin 930

123 (chicken egg)

Azurin 880

124 {Pseudomonas fluorescens)

Azurin 970

125 {Pseudomonas polym yxa)

Biotin carboxyl carrier protein 1,300

{Escherichia coli)

Blastokinin 1,030

127 (rabbit)

Bradykininogen 980

128 (bovine)

a-Bungarotoxin 1,040

129 {Bungarus multicintus)

130 (human plasma)

Calcitonin 1,080

(bovine)

132 (human)

133 (porcine)

Calcitonin 860

134 (salmon)

Calcium-binding protein 780

135 (bovine adrenal medulla)

Calcium-binding protein 930

(chick duodenal mucosa)

Calcium-binding protein-B (parvalbumin) 890

137 {Cyprinus carpio muscle)

Calcium-binding protein 740

138 (porcine brain)

Carbamyl phosphate synthetase 960

139 {Escherichia coli B)

140 (bovine)

Carbonic anhydrase {Gallus domesticus)

Protein

Carbonic anhydrase (parsley)

Average hydrophobicity Reference

142 Carbonic anhydrase (sheep)

143 Carbonic anhydrase B (bovine)

144 Carbonic anhydrase B (equine)

145 Carbonic anhydrase B (Macaca mulata)

146 Carbonic anhydrase B (porcine)

147 Carbonic anhydrase C (equine)

148 Carbonic anhydrase C (porcine)

1,010

149 j3-Carboxy-cis,cis-muconate lactonizing enzyme (.Pseudomonas putida)

150 7 -Carboxymuconolactone decarboxylase (Pseudomonas putida)

1,170

151 Carboxypeptidase A (bovine pancreas)

152 Carboxypeptidase A (Penaeus setiferus)

153 Carboxypeptidase B {Penaeus setiferus)

154 Carboxypeptidase B (Protopterus aethiopicus)

155 Procarboxypeptidase B {Protopterus aethiopicus)

156 Carboxypeptidase B (dogfish pancreas)

1,070

157 Carboxypeptidase Y (yeast)

1,050

158 Carboxytransphosphorylase (propionic acid bacteria)

159 Catalase (bovine liver)

160 Colchicine-binding protein (sea urchin)

161 Colchicine-binding protein (porcine brain)

162 Chorionic gonadotropin-a (human)

163 Chorionic gonadotropin-j3 (human)

1,120

164 Chorismate mutase-prephenate dehydratase {Escherichia coli K-12)

165 Chymoelastase, lysine free {Streptomyces griseus K-l)

Protein

Chymoelastase, guanidine stable {Streptomyces griseus K-l)

Average hydrophobicity

Reference

167 Chymotrypsin, anionic (fin whale)

1,060

168 Chymotrypsin II (human)

169 Chymotrypsinogen A (dogfish)

170 Chymotrypsinogen B (bovine pancreas)

171 Chymotrypsinogen B (porcine pancreas)

172 Chymotrypsinogen C (porcine pancreas)

173 Cocoonase (Antheraea pernyi)

174 Cocoonase (Antheraea polyphemus)

175 Prococoonase (Antheraea polyphemus)

176 Colicin Ia-CA53 CEscherichia coli)

177 Colicin Ib-P9 CEscherichia coli)

178 Collagen (chicken tendon)

179 Collagen, a-fraction (calf skin)

180 Collagen, spongin B (sponge)

181 Collagen (sturgeon swim bladder)

182 Collagenase (Uca pugilator)

183 Conalbumin (chicken)

184 Corrinoid protein {Clostridium thermoaceticum)

185 Creatine kinase (Cyprinus carpio L.)

186 Creatine kinase (human)

187 Crotonase {Clostridium acetobutylicum)

188 Cro toxin {Crotalus terrificus terrificus)

189 Cystathionase (rat liver)

190 Cytochrome b s (bovine liver)

Protein

Cytochrome b 5 (equine liver)

Average hydrophobicity Reference

192 Cytochrome b 5 (porcine liver)

193 Cytochrome c (horse heart)

1,050

194 Cytochrome c (chicken)

1,050

195 Cytochrome c (cow, pig, sheep)

1,020

196 Cytochrome c (dog)

1,070

197 Cytochrome c (kangaroo)

1,130

198 Cytochrome c (king penguin)

1,060

199 Cytochrome c (Macaca mulata)

1,060

1,060

1,070

1,070

203 Cytochrome c (rattlesnake)

1,050

204 Cytochrome c (Saccharomyces)

1,040

205 Cytochrome c (tuna)

1,050

206 Cytochrome c (turkey)

1,050

207 Cytochrome CA (Humicola lanuginosa)

208 Cytochrome C 3 (Desulfovibrio desulfuricans)

209 Cytochrome C 3 CDesulfovibrio gigas)

213 Daunorubicin reductase (rat liver)

214 3-Deoxy-D-arabinoheptulosonate 7-phosphate synthetase-chorismate mutase

215 Deoxycytidylate deaminase (T2 r+ bacteriophage)

Protein Average

hydrophobicity Reference

216 Deoxyribonuclease 930

217 (bovine pancreas)

Deoxyribonuclease A 970

218 (bovine pancreas)

Deoxyribonuclease B 980

219 (bovine pancreas)

Deoxyribonuclease C 980

Deoxyribonuclease II 1,050

(porcine spleen)

Deoxyribonucleic acid ligase 970

223 (calf spleen)

a-Dialkylamino transamidase 930

224 (Pseudomonas cepacia)

Dihydrofolate reductase 1,030

225 (T4 bacteriophage)

Dihydrofolate reductase 1,030

(Escherichia coli MB 1428)

227 (Lactobacillus casei)

Dihydrofolate reductase 1,060

228 (Streptococcus faecium)

3,4-Dihydroxyphenylacetate-2,3-oxygenase 980

229 (Pseudomonas ovalis)

Dopamine-0-hydroxylase 950

230 (bovine adrenal)

Elastin 940

(bovine aorta)

Elastin 990

232 (bovine ear cartilage)

Elastin 980

233 (bovine ligamentum nuchae)

Encephalitogenic A-l protein 850

234 (bovine brain)

Encephalitogenic A-l protein 820

235 (human brain)

Endopolygalac tu ronase 850

(Verticillium albo-atrum)

Enolase 970

237 (monkey muscle)

Enolase 980

238 (Onkorhynchus beta)

Enolase 930

239 (Onkorhynchus kisutch)

Enolase 990

240 (rabbit muscle)

Enolase 900 (Thermits X-l)

Protein Average

hydrophobicity Reference

241 Enolase {Thermus aquaticus YT-1)

242 Enolase (yeast)

243 Entero toxin C 0Staphylococcus 137)

244 Entero toxin E {Staphylococcus aureus FRI-326)

245 Entero toxin A {Staphylococcus aureus 13N-2909)

246 Erythrocuprein (human)

247 Esterase (pig liver)

248 Estradiol dehydrogenase (human placenta)

249 Factor III lac {Staphylococcus aureus)

250 Factor VIII (bovine plasma)

1,030

251 Factor VIII (human plasma)

252 Ferredoxin {Chlorobium thiosulfatophilum)

253 Ferredoxin {Clostridium pasteurianium)

254 Ferredoxin {Chromatium)

255 Ferredoxin {Cyperus rotundus)

256 Ferredoxin {Desulfovibrio gigas)

257 Ferredoxin (iSpinacea)

258 Ferredoxin {Scenedesmus)

259 Ferredoxin I {Azotobacter vinelandii)

1,050

260 Ferredoxin I {Bacillus polymxa)

261 Ferredoxin II {Bacillus polymxa)

262 Ferritin (horse spleen)

263 Ferritin (tadpole red blood cell)

264 Fibrinogen B (lobster)

265 Fibroin {Bombyx mori)

Protein Average

hydrophobicity Reference

266 Fibroin (Tussah)

267 Ficin II (Ficus glabrata)

268 Ficin III (Ficus glabrata)

269 Flagellin (Proteus vulgaris)

270 Flagellin (Salmonella SJ 25)

271 Flagellin (Salmonella typhimurium)

272 Flavodoxin (Qostridium MP)

273 Flavodoxin (Clostridiam pasteurianiu m )

274 Flavodoxin (Desulfovibrio gigas)

275 Flavodoxin (Desulfovibrio vulgaris)

276 Flavodoxin (Peptostreptococcus elsdenii)

277 Follicle stimulating hormone (ovine)

278 A-formimino-L-glutamate iminohydrolase (Pseudomonas ATCC 11299b)

279 Fructose-1,6 -diphosphatase (porcine kidney)

280 0 -Galactosidase (Escherichia coli)

281 Gastricin (human)

282 Gastricin (porcine)

283 Gliadin SP 2-2 (Cappelle 1966 flour)

1,300

284 Gliadin SP 2-1 (wheat, Wichita 1963)

1,250

285 Gliadin SP 2-2 (wheat, Wichita 1963)

1,180

286 Gliadin SP 2-3 (wheat, Wichita 1963)

1,180

287 Globulin, 0.6 S y 2 (human plasma)

1,090

288 Glucagon (bovine)

289 Glutamate decarboxylase (Escherichia coli)

1,080

290 Glutamate dehydrogenase (bovine liver)

Protein

Glutamate dehydrogenase (Neurospora crassa)

Average hydrophobicity Reference

292 Glutaminase-asparaginase CAchromobacteraceae)

293 Glutamine synthetase (rat liver)

294 7 -Glutamyl cyclo transferase (porcine liver)

295 Glyceraldehyde-3-phosphate dehydrogenase CBacillus stearothermophilus)

296 Glyceraldehyde-3-phosphate dehydrogenase (bovine liver)

297 Glycerol-3-phosphate dehydrogenase (rabbit muscle)

1,040

298 Glycocyamine kinase (Nepthys coeca)

299 Glycogen phosphorylase (Baker’s yeast)

1,050

300 Glycogen phosphorylase {Carcharhinus falciformis)

1,080

301 Glycogen phosphorylase (human)

1,060

302 Glycogen phosphorylase (rabbit liver)

1,060

303 Glycogen phosphorylase (rat)

1,070

304 Glycogen synthetase (porcine kidney)

305 7 -Glycoprotein (human plasma)

1,070

306 Growth hormone (human)

307 Haptoglobin, a 2-chain (human plasma)

308 Haptoglobin, c^g-chain (human plasma)

309 Haptoglobin, /J-chain (human plasma)

1,020

310 Hemagglutinin CLens esculenta Muench)

1,000

311 Hemagglutinin I (Pisum sativum L. var. pyram)

312 Hemagglutinin 11 (Pisum sativum L. var. pyram )

313 Hemagglutinin (Robina pseudoaccacia)

314 Hemagglutinin 11 (snail)

1,070

315 Hemagglutinin (soy)

Protein Average

hydrophobicity Reference

316 Hemagglutinin 950

317 (Ulex europeus)

Hemerythrin 1,170

318 {Golfingia gouldii)

319 (Cancer magister)

Hemocyanin 980

320 (Crustaceae C. sapidus)

Hemocyanin 980

{Crustaceae E. spinifrons)

Hemocyanin 980

322 {Crustaceae H. vulgaris)

Hemocyanin 980

323 {Crustaceae P. vulgaris)

Hemocyanin 1,050

324 {Mollusca E. moschata)

325 {Mollusca M. brandaris)

{Mollusca M. tranculus)

Hemocyanin 1,050

327 {Mollusca 0 . macropus)

Hemocyanin 1,080

328 {Mollusca O. vulgaris)

Hemocyanin 980

329 {Xiphosura L . polyphemus)

Hemoglobin 980

330 {Ascaris body wall)

{Entosphenus japonicus)

Hemoglobin 870

332 {Glycera dibranchiata)

333 {Catostomus clarkii)

Hemoglobin, a-chain 960

334 (human)

Hemoglobin, 7 -chain 960

335 (bovine)

Hemoglobin, 7 -chain 960

(human)

Hemoglobin, F-l 1,170

337 {Eptatretus burgeri)

Hemoglobin, F-2 1,160

338 {Eptatretus burgeri)

Hemoglobin, F-3 1,140

339 {Eptatretus burgeri)

Hemoglobin, F-4 1,040

340 {Eptatretus burgeri)

Protein

Hemopexin (rabbit)

Average hydrophobicity

Reference

342 High potential iron sulfur protein (Chromatium vinosum D)

343 High potential iron sulfur protein (Thiocapsa pfennigii)

344 Histidine: ammonia lyase (Pseudomonas ATCC 11299b)

345 Histidine-binding protein 0 Salmonella typhimurium)

346 Histidine decarboxylase CLactobacillus 30a)

347 L-Histidinol phosphate aminotransferase 0 Salmonella typhimurium )

348 Histidyl-tRNA synthetase 0 Salmonella typhimurium)

349 Histone III (calf thymus)

350 Histone III (Letiobus bubalus)

351 Histone III (pea)

352 Histone III (rainbow trout)

353 Hyaluronidase (bovine testicular)

1,030

354 Hydrogenase (<Clostridium pasteurianium W5)

1,160

355 3-Hydroxyacyl coenzyme A dehydrogenase (porcine heart muscle)

356 0 -Hydroxybutyrate dehydrogenase (bovine heart mitochondria)

357 a 1 -Hydroxysteroid dehydrogenase CPseudomonas testosteroni)

358 17-0-Hydroxysteroid dehydrogenase (human placenta)

359 Immunoglobulin, Eu heavy chain (human plasma)

360 Immunoglobulin, Eu light chain (human plasma)

361 Immunoglobulin, New \-chain (human plasma)

362 Inorganic pyrophosphatase (yeast)

1,130

363 Insulin (bovine)

364 Insulin (cod)

365 Invertase {Saccharomyces FH4C)

Protein Average

hydrophobicity Reference

366 Isoamylase I (porcine pancreas)

367 Isoamylase II (porcine pancreas)

368 Isocitrate dehydrogenase (Azotobacter vinelandii ATCC 9104)

369 Isocitrate dehydrogenase (porcine liver)

370 Isomerase I (rabbit)

1,080

371 Isomerase II (rabbit)

372 Keratinase (Trichophyton mentagrophytes)

373 A5 -3-Ketosteroid isomerase CPseudomonas testosteronii)

374 a-Lactalbumin (bovine milk)

1,050

375 Lactoferrin (bovine)

376 /3-Lactoglobulin (caprid)

1,040

377 /3-Lactoglobulin A (bovine)

1,070

378 /3-Lactoglobulin A (ovine)

1,050

379 /3-Lactoglobulin B (bovine)

1,060

380 /3-Lactoglobulin B (ovine)

1,050

381 /3-Lactoglobulin C (bovine)

1,070

382 Lactoperoxidase (bovine milk)

1,080

383 Lectin, a-D-galactosy 1-binding (Bandeiraea simplicifola)

384 Leghemoglobin I (soy bean root nodule)

385 Leghemoglobin II (soy bean root nodule)

386 Leucine aminopeptidase (bovine lens)

387 Lipase (rat pancreas)

388 /3-Lipolytic hormone (porcine pituitary)

389 7 -Lipolytic hormone (sheep)

390 a-Lipovitellin (chicken egg yolk)

Protein

Luciferase (Renilla reniformis)

Average hydrophobicity

Reference

392 Luciferase-a (MAV)

393 Luciferase-0 (MAV)

394 Luciferase-a CPhotobacterium flscheri)

395 Luciferase-/3 CPhotobacterium flscheri)

396 Luteinizing hormone-a chain (equine)

1,070

397 Luteinizing hormone - 0 chain (equine)

398 Lysine decarboxylase CEscherichia coli)

1,080

399 L-Lysine monooxygenase (Pseudomonas fluorescens)

1,040

400 Lysostaphin {Staphylococcus aureus)

401 Lysozyme (Chalaropsis)

402 Lysozyme, chick type (black swan)

403 Lysozyme, goose type (black swan)

404 Lysozyme (chicken)

405 Lysozyme (papaya)

1,080

406 Lysozyme (turkey)

407 Lysyl: tRNA ligase {Escherichia coli)

408 Lysyl: tRNA ligase (yeast)

1,040

409 a-Lytic protease {Sorangium sp.)

410 0 -Lytic protease {Sorangium sp.)

411 Malate dehydrogenase {Bacillus subtilis)

412 Malate-lactate transhydrogenase {Micrococcus lactilyticus)

413 Malate-vitamin k reductase {Mycobacterium phleii)

414 L-Malic enzyme (Escherichia coli)

415 0 -Melanocyte stimulating hormone (bovine)

1,180

Protein Average

hydrophobicity Reference

416 Melilotate hydroxylase 970

417 CPseudomonas sp.)

Methionyl-tRNA synthetase 1,040

418 CEscherichia coli)

/3-Methyl aspartase 980

419 {Clostridium tetanomorphum)

0 -Methylcrotonylcoenzyme A carboxylase 890

420 {A chromobacter)

Methylmalonatesemialdehydedehydrogenase 1,030

{Pseudomonas aeruginosa)

Molydbenum-iron protein 1,010

422 (soy bean root nodule bacteroid)

Monellin 1,140

423 {Dioscoreophyllum cumminsii)

Motilin 1,020

424 (porcine intestinal mucosa)

cis,cis-Muconate lactonizing enzyme 990

425 {Pseudomonas putida)

Muconolactone isomerase 1,070

{Pseudomonas putida)

Mutarotase 850

427 (bovine kidney cortex)

Myoglobin 1,000

428 (human)

Myoglobin 1,040

429 (whale)

Myoglobin 1,030

430 {Zalophus califomianus)

Myohemerythrin 1,090

{Dendrostamum pyroides)

Myosin 880

432 (bovine heart)

Myosin 860

433 (cod)

Myosin 890

434 (rabbit)

Myosin 880

435 (tuna)

Neocarzinostatin 750

{Streptomyces carzinostaticus F-41)

Neurophysin I 850

437 (bovine pituitary)

Neurophysin II 830

438 (bovine pituitary)

Neurophysin III 820

439 (bovine pituitary)

Neurotoxin I 1,070

440 {Androctonus australis)

Neurotoxin II {Androctonus australis)

Protein

Neurotoxin III (Androctonus australis)

Average hydrophobicity

Reference

442 Neurotoxin I {Leiurus quinquestriatus quinquestriatus)

1,040

443 Neurotoxin II CLeiurus quinquestriatus quinquestriatus)

444 Neurotoxin III (.Leiurus quinquestriatus quinquestriatus)

1,030

445 Neuro toxin IV CLeiurus quinquestriatus quinquestriatus)

1,050

446 Neurotoxin V CLeiurus quinquestriatus quinquestriatus)

447 Nuclease CMicrococcus sodonencis ATCC 11880)

448 Nuclease {Staphylococcus)

449 Nucleoside diphosphokinase (Brewer’s yeast)

1,030

450 Nucleoside phosphotransferase-A-chain (carrot)

451 Nucleoside phosphotransferase-B-chain (carrot)

452 5'-Nucleotidase {Escherichia coli)

453 Ornithine transcarbamylase (bovine liver)

1,040

454 Ornithine transcarbamylase {Streptococcus faecalis)

455 Ovalbumin (chicken egg)

456 Ovomacroglobulin (chicken egg)

1,040

457 Ovomucin (chicken egg)

458 Ovomucoid (chicken egg)

459 Ovotransferrin (chicken egg)

460 2-Oxoglutarate dehydrogenase (porcine heart)

461 Oxytocin (mammalian)

1,290

462 Papain (papaya)

1,030

463 Parathyroid hormone (bovine)

464 Parvalbumin (rabbit skeletal muscle)

465 Penicillocarboxypeptidase-S {Penicillium janthinellum)

Protein Average

hydrophobicity Reference

466 Pepsin 940

467 (bovine)

Pepsin 930

468 (human)

Pepsin I 910

469 (Rhizopus chinertsis)

Pepsin II 910

470 CRhizopus chinensis)

Pepsinogen A 960

(bovine)

Pepsinogen A 920

A ll (Mustelus cams)

Pepsinogen A 970

473 (porcine)

474 (porcine)

Phenylalanine ammonia lyase 1,030

475 {Solarium tuberosum)

Phenylalanine ammonia lyase 940

{Zea mays L.)

Phenylalanine hydroxylase 930

A ll (rat liver)

Phosphatidyl serine decarboxylase 1,050

478 {Escherichia coli)

Phosphoenol pyruvate carboxykinase 1,030

479 (yeast)

Phosphofructokinase 940

480 (chicken liver)

(rabbit muscle)

482 (human)

483 (rabbit muscle)

Phosphoglycerate kinase 980

484 (human erythrocyte)

Phospholipase A 910

485 {Bitis gabonica venom)

Phospholipase At 1,030

{Crotalus adamanteus)

Phospholipase A2 920

487 {Crotalus atrox)

Phospholipase A 950

488 {Laticuda semifasciata)

Phosphorylase 1,070

489 (frog skeletal muscle)

Phycocyanin 910

490 CP. calothricoides)

Phycocyanin {S. lividicus)

1,040

Protein Average

hydrophobicity Reference

491 Phycoerythrin 830

492 {P. tenera)

493 (oat)

Plastocyanin 880

494 (parsley)

Prealbumin 990

495 (human serum)

Prealbumin, Pt 1-1 990

(monkey)

497 (monkey)

498 (bovine)

499 (Squalus acanthias)

Progesterone-binding protein 1,040

500 (guinea pig plasma)

Prohistidine decarboxylase 990

(Lactobacillus 30a)

Prolactin 950

502 (ovine pituitary)

Protease 940

503 (.Bacillus thermoprotolyticus)

Protease 940

504 {Mucor miehei CBS 370.65)

Protease 900

505 {Staphylococcus aureus V 8 )

Protease - 700

(Streptomyces griseus)

Protease-acid 950

507 {Rhizopus chinensis)

Protein kinase modulator 720

508 (lobster tail muscle)

Prothrombin 960

509 (bovine)

510 (Rana pipiens pipiens)

Putidaredoxin 910

{Pseudomonas putida)

Putrescine oxidase 860

512 {Micrococcus rubens)

513 (bovine skeletal muscle)

Quinonoid dihydropterin reductase 890

514 (sheep liver)

Retinol-binding protein 960

515 (human)

Retinol-binding protein (monkey)

Protein Average

hydrophobicity Reference

516 Rhodopsin (bovine)

517 Riboflavin-binding protein (chicken)

518 Ribonuclease CAspergillus fumigatus)

519 Ribonuclease CBacillus subtilis)

520 Ribonuclease (bovine pancreas)

521 Rubonuclease (ovine pancreas)

522 Ribonuclease Ch. {Chalaropsis sp.)

523 Ribonuclease N (Neurospora crassa)

524 Ribonuclease Rt (Rhizopus oligosporus)

525 Ribonuclease R 2 CRhizopus oligosporus)

526 Ribonuclease Tj CAspergillus oryzae)

527 Ribonuclease Uj (UstUago sphaerogerta)

528 Ribonucleotide reductase (Lactobacillus leichmanii)

529 Ribulose diphosphate carboxylase (,Hydrogenomonas eutropha)

530 Ribulose diphosphate carboxylase CHydrogenomonas facilis)

531 Ribulose diphosphate carboxylase (Rhodospirillum rubrum)

532 Rubredoxin {Clostridium pasteurianum)

533 Rubredoxin {Micrococcus aerogenes)

534 Rubredoxin {Pseudomonas oleovorans)

535 D-Serine dehydratase {Escherichia coli)

536 Streptokinase (human plasma)

537 Subtilisin BPN {Bacillus subtilis)

538 Succinyl coenzyme A synthetase {Escherichia coli)

539 Sucrose synthetase {Phaseolus aureus)

1,040

540 Superoxide dismutase {Neurospora crassa)

Protein Average

hydrophobicity Reference

541 Thermolysin CBacillus thermoproteolyticus)

542 Thioredoxin (T-4 bacteriophage)

1,150

543 Thioredoxin II (yeast)

544 Thrombin (bovine)

1,040

545 Thymidylate synthetase (T-2 bacteriophage)

1,140

546 Thyroglobulin (calf)

547 Thyroglobulin (human)

548 Thyroglobulin (porcine)

549 Thyroglobulin (rabbit)

550 Thyroglobulin (sheep)

551 Thyroid stimulating hormone - a-chain (human)

552 Thyroid stimulating hormone - /3-chain (human)

1,170

553 Toxin FVII (Dendroaspis angusticeps)

554 Toxin o l (Dendroaspis polylepsis)

555 Toxin y (.Dendroaspis polylepsis)

556 Toxin 4 {Enhydrina schistosa)

557 Toxin 5 CEnhydrina schistosa)

558 Toxin (Laticauda colubrina)

559 Toxin (Laticauda laticauda)

560 Toxin a (Laticauda semifasciata)

561 Toxin b (Laticauda semifasciata)

562 Toxin {Naja haje haje)

563 Toxin b {Naja melanoleuca)

1,090

564 Toxin d {Naja melanoleuca)

565 Toxin {Naja naja atra)

Protein

Toxin (Naja nigricollis)

Average hydrophobicity

Reference

567 o-Toxin A {Staphylococcus aureus Woods 46)

568 a-Toxin B {Staphylococcus aureus Woods 46)

569 Transaminase B {Salmonella typhimurium)

570 Transcortin (guinea pig)

571 Transcortin (human)

572 Transcortin (rabbit)

573 Transcortin (rat)

1,030

574 Transferrin (bovine)

575 Transferrin (equine)

576 Transferrin (human)

577 Transferrin (porcine serum)

578 Transferrin (rabbit serum)

579 Triose phosphate dehydrogenase {Bom bus nevadensis)

1,040

580 Triose phosphate dehydrogenase (honey bee)

581 Triose phosphate dehydrogenase (lobster)

582 Triose phosphate dehydrogenase (porcine)

583 Triose phosphate isomerase-I (human erythrocyte)

584 Triose phosphate isomerase-III (human erythrocyte)

585 Triose phosphate isomerase (rabbit muscle)

586 Triose phosphate isomerase (yeast)

587 Troponin-C (rabbit muscle)

588 Troponin-T (rabbit muscle)

1,040

589 Trypsin {Evasterias trochelli)

590 Trypsin (lungfish)

Protein

Trypsin (human)

Average hydrophobicity

Reference

592 Trypsin, anionic (human)

593 Trypsin (porcine)

594 Trypsin (sheep)

595 Trypsin (shrimp)

596 Trypsin (iStreptomyces griseus)

597 Trypsin inhibitor (Ascaris lumbricoides suis)

598 Trypsin inhibitor (bovine pancreas)

1,150

599 Trypsin inhibitor (porcine pancreas)

600 Trypsin inhibitor (bovine pancreas)

1,070

601 Trypsin inhibitor I (Phaseolus vulgaris)

602 Trypsin inhibitor II CPhaseolus vulgaris)

603 Trypsinogen (bovine)

604 Trypsinogen (dogfish)

605 Trypsinogen (lungfish)

606 Trypsinogen, anionic (porcine)

607 Trypsinogen (sheep)

608 Tryptophan synthetase A CEscherichia coli)

1,060

609 Tryptophan synthetase-a-chain (Aerobacter aerogenes)

1,060

610 Tryptophan synthetase - a-chain CBacillus subtilis)

611 Tryptophan synthetase - a-chain CSalmonella typhimurium )

612 Tryptophan synthetase - /3-chain CBacillus subtilis)

613 Tryptophanase (Bacillus alvei)

614 Tryptophanase (.Escherichia coli B/lt7-A)

1,030

615 Tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1,060

Protein Average

hydrophobicity Reference

616 Urease (jackbean meal)

617 Urokinase S-l (human urine)

1,030

618 Urokinase S-2 (human urine)

619 Valine :tRNA ligase (yeast)

1,080

620 Vasopressin, lysine (mammalian)

Compiled by C. C. Bigelow and M. Channon.