ABSTRACT
Many organic materials such as polymers [5], liposomes, and micelles have been investigated as drug delivery carriers. However, unsolved problems regarding these organic systems continue to exist. These problems include low chemical stability, swelling, susceptibility to microbiological contamination, and inadequate control over the drug release rate. The release properties of many biodegradable polymer-based drug delivery systems are dependent on the hydrolysis-induced erosion of the carrier structure [2,3]. Such systems usually require the use of organic solvents for drug loading, which could sometimes trigger undesirable modi cations of the structure or the function or both of the encapsulated molecules.
