ABSTRACT

The Case of Wine ................................................................................... 422 References ......................................................................................................... 427

Diet is one of the most important lifestyle factors affecting the incidence and severity of several diseases, including cardiovascular disease [1]. Multiple risk factors for atherosclerosis and cardiovascular disease include disordered lipid profi les, homocysteine, smoking, elevated blood sugar, C-reactive protein, hypertension, and genetic predisposition [2-4]. Many of them act in a coordinated way,

through multiple infl ammatory pathways [5], and can act synergistically to increase relative risk.