ABSTRACT

direct analysis in real time (DART) is one of the ionization techniques instrumental in moving the sample from the vacuum to the ambient environment. The sample is placed or held in the path of the plasma (containing ions, metastable atoms, electrons and molecules) generated from the DART source using helium or nitrogen. DART-Time Of Flight (TOF)-mass spectrometry (MS) combined with principal component analysis (PCA) is an efficient and high-throughput method that allows studying variation in samples. As DART-MS fingerprinting is a very fast method, we have used this method for the fingerprinting of Phyllanthus amarus samples collected from three different locations in India, viz., Kolkata from the state of West Bengal, Jabalpur from the state of Madhya Pradesh and Lucknow from the state of Uttar Pradesh during the period of 2009–2011.