ABSTRACT

Nanosensors based on surface plasmon resonance (SPR) and localized surface plasmon (LSPR), including colorimetric devices, are described. Among fiber-optic nanosensors, Fabry-Perot reflectometric optochemical nanosensor employing SWCNTs and optical fibers, in-fiber nanocavity sensor and fiber-optic nanosensors for probing living cells stand out prominently. A nanograting-based optical accelerometer is discussed. Examples of fluorescent pH-sensitive nanosensors are renewable glass nanopipette with fluorescent dye molecules, ratiometric pH nanosensor and pH-sensitive microcapsules with nanoparticle incorporation in the walls. Disadvantages of optical fiber and fluorescent nanosensors for living cell studies are indicated. PEBBLE nanosensors are useful for exploring the intracellular environment. Quantum dots serve as fluorescent labels. Several quantum dot FRET-based probes have been developed, namely probes for determination of protein, protease, maltose and dissociation constant between Rev and RRE. Electrochemiluminescent nanosensors have the capability for remote detection, while crossed zinc oxide nanorods act as resistive UV nanosensors.