ABSTRACT
This conclusion summarizes basic results described in this book. The tumor irradiation efficiency can be measured by the difference between the expected survival probabilities for normal and neoplastic cells. The following problems have been formulated: To find the precise upper bound of the functional over certain classes of admissible response functions; and to construct for model 1 an optimal irradiation scheme within a prescribed set of admissible irradiation schemes. Numerical experiments reveal uniformity of the optimal irradiation scheme. As simulation study shows, the optimal regimen retains (at least in some situations) a tendency to be uniform with respect to the value of dose per fraction even in the presence of transient processes of radiation damage formation and postirradiation recovery of normal and neoplastic cells.
