The synergistic design process plays a major role in the creation of next-generation sustainable buildings that integrate natural processes and programmatic requirements and synthesize into architectural design. In any project development today, when the potentials of passive strategies are fully exhausted – depending upon the climatic and other conditions – then only the relatively low-energy design strategies and active strategies available should be explored to meet occupants’ comfort demand.

The climatic matrix differs considerably from region to region, and in those differences lie the origins of environmentally sustainable building design, which has become a larger concern for architecture’s avant-garde and mainstream alike. Today’s designers can access an enormous amount of climate data that is light-years ahead in its accuracy and precision. However, the real challenge lies in extracting and assessing the pertinent climate data to respond with intelligent design decisions. This chapter aims to present a narrative summation of macroclimate data, wind roses, and sun path diagrams for the major US cities, which can be used to conduct climate analysis; then the summary moves into specific data to inform sustainable building design and renewable energy system application.