ABSTRACT
Chronic lymphocytic leukemia (CLL) is a low-grade lymphoproliferative disorder of mature B cells characterized by lymphocytosis (≥5 × 109/L; >3 months); expression of CD5, CD23, and CD200; and involvement of blood, bone marrow (BM), spleen, and lymph nodes [1–6]. Patients with a clonal CLL-like cell count <5 × 109/L and without adenopathy, organomegaly, or other extramedullary disease are classified as monoclonal B-cell lymphocytosis (MBL).
