Numerous genes that cause hypertension can be specific for treatment with a drug, a supplement, an electrolyte, and with a diet or nutrition. The genetic testing will allow the doctor to measure many of the genes that cause hypertension and provide a more direct, personalized, and precision treatment program without any of the guess work. Genetics and nutrigenomics provide us with an expanded perspective on the prevention and treatment of hypertension and cardiovascular disease. In cardiovascular management, nutrigenomics encompasses genetic testing and the identification of single nucleotide polymorphisms, nutrient-genetic interactions, and how the genes express themselves. Most genetic expression is driven by inflammation, and the majority of the genes, once turned on, promote an inflammatory response. Most of the active areas on genes associated with hypertension, heart attack, heart failure, and coronary heart disease are expressed through inflammation, oxidative stress, and immune-vascular dysfunction.