ABSTRACT
At present, the development of Nitric Oxide (NO)-sensing devices relying on available NO detection techniques is particularly demanding for the direct measure of the NO concentration in the environment as well as in the exhaled breath of mammals, including humans. Besides atmospheric NO determination, an accurate measurement of the NO level in exhaled breath gives a direct measure of eosinophilic inflammation, which provides diagnostic information about a patient with asthma. Besides, Karunakaran et al. discovered a virtual platform based on nanoengineered electrochemical analyzer for exhaled NO gas. The NO biosensor was constructed by using Cu and ZnSOD immobilized on carbon nanotubes on a polypyrrole-coated platinum surface. Optical techniques are used for sensing of various gases for decades due to their high precession and remarkable selectivity toward target molecules. The techniques are basically used for biomedical applications for fast response and compact design for achieving the greater challenge.
