ABSTRACT

Enilconazole is an imidazole antifungal agent used in veterinary medicine and as agricultural fungicide, particularly in the growing of citrus fruits. In veterinary medicine, it is employed in topical preparations for the treatment of fungal infections in cattle, horses and dogs caused by Trichophyton and Microsporum species. There is also one case report of occupational allergic contact dermatitis to enilconazole in a metalworker from its presence in a water-based metalworking fluid. In a literature review up to 1994, the authors identified 105 reported patients who had a positive patch test reaction to at least one imidazole derivative, ranging from 51 reactions to miconazole to one reaction each to enilconazole and bifonazole.