ABSTRACT
This chapter provides monographs of flurandrenolide which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. In the United Kingdom, from 1988 to 1991, 528 selected patients with a positive patch test to tixocortol pivalate or suspected of corticosteroid allergy were patch tested with flurandrenolide 20% pet. and 2 patients (0.4%) had a positive reaction. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
