ABSTRACT
Halquinol is a combination of hydroxyquinolines currently described as 5,7-dichloro-8-quinolinol 14%, 5-chloro-8-quinolinol 42%, 7-chloro-8-quinolinol 10% and 8-hydroxyquinoline 34% (PubChem). ChemIDPlus describes it as 5,7-dichloro-8-quinolinol, mixture with 5-chloro-8-quinolinol and 7-chloro-8-quinolinol. It is or was used in antiseptic preparations, sometimes also in topical corticosteroid preparations. This chapter provides monographs of halquinol which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
