ABSTRACT
Iodoform is an organo-iodine compound with the formula CHI3 and a tetrahedral molecular geometry. When iodoform decomposes it releases iodine in nascent state (96.7% of iodine) when in contact with secretions, endodontic infections or granulation tissue. It is a relatively water-insoluble yellow solid powder or crystals with penetrating odor and unctuous feel, that is chemically reactive in free-radical reactions. A study from the United Kingdom showed that 12% of patients previously exposed to bismuth iodoform paraffin paste (BIPP) may have become sensitized, which makes it a frequent allergen. In Ipswitch, United Kingdom, in the period 2000-2007, 237 patients previously undergoing surgery, were patch tested with BIPP (tested pure). In the UK, between 1985 and 2002, 179 patients with chronic inflammatory ear disease were patch tested with iodoform 10% pet. and there were 3 (1.7%) positive reactions.
