ABSTRACT
Mesulfen is a thianthrene that was formerly used in the treatment of scabies and dermatomycosis. Topical preparations with mesulfen are apparently still available in some countries, e.g. as a parasiticide and antipruritic in a range of skin disorders including acne, scabies, and seborrhoea. This chapter provides monographs of mesulfen which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
