ABSTRACT
Methylphenidate is a synthetic central nervous system stimulant. It appears to activate the brain stem arousal system and cortex to produce its stimulant effect and, in some clinical settings, may improve cognitive function. Methylphenidate is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy. This chapter provides monographs of methylphenidate which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section and contact allergy (general population, patients with dermatitis, case reports and case series). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
