ABSTRACT
Amine fluorides, used in toothpastes to deliver fluoride to the teeth and combat caries, were developed at the end of the 1950’s. The most widely used amine fluorides are olaflur (though only in one brand) and octadecenylammonium fluoride (synonym: dectaflur). This chapter provides monographs of olaflur which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
