ABSTRACT
Piketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) from the arylpropionic acid group, which prevents the synthesis of prostaglandins and other prostanoids through competitive and reversible inhibition of cyclooxygenase. This chapter provides monographs of piketoprofen which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
