ABSTRACT
Prednicarbate is a synthetic non-halogenated double-ester derivative of the corticosteroid prednisolone. This chapter provides monographs of prednicarbate which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy. As this corticosteroid has never been used in pharmaceuticals in Belgium, these positive reactions must all be considered cross-reactions to other corticosteroids.
