ABSTRACT
Prilocaine is an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. It is used for local anesthesia by infiltration and is the most often used local anesthetic in dentistry. This chapter provides monographs of prilocaine which have caused contact allergy/allergic contact dermatitis. The monographs present: identification section; contact allergy (general population, patients with dermatitis, case reports and case series); cross-reactions; patch test sensitization; photocontact allergy; and immediate contact reactions (contact urticaria). The identification section presents IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing. The chapter also covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy.
