ABSTRACT
From January 1990 to June 2008, in Leuven, Belgium, 315 patients were diagnosed with contact allergy to/allergic contact dermatitis from corticosteroids (CSs) from routine patch testing with a baseline series including tixocortol pivalate, budesonide, hydrocortisone butyrate and prednisone caproate, patch testing with patients’ own CS preparations, and testing those with proven contact allergy to a corticosteroid or strongly suspected of CS allergy later with a series of 66 CSs, including two sex hormones. In reviewing the Japanese literature up to 1994, 43 patients with allergic contact dermatitis from topical corticosteroid were identified, including one caused by betamethasone sodium phosphate. Cutaneous adverse drug reactions from systemic administration of betamethasone sodium phosphate caused by type IV hypersensitivity, including systemic contact dermatitis, are planned to be discussed in Volume IV of the Monographs in Contact Allergy series on Systemic drugs.
