ABSTRACT
Cromoglicic acid is a mast cell stabilizer with anti-inflammatory activity. It probably interferes with the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions. In eye drops, it has been used to treat allergic conjunctivitis and vernal keratoconjunctivitis and it is useful as nasal spray in patients with allergic rhinitis. A 32-year-old woman was prescribed eye drops containing 4% sodium cromoglycate for complaints of ocular discomfort, with severe itching and burning sensations, photophobia and conjunctival injection, which were ascribed to the cleaning product of her contact lenses. She continued to use the same contact lenses and cleaning solution. Positive patch test were observed to the eye drops, the cleaning solution and thimerosal, which was the preservative in the cleaning solution. Avoiding the cleaning solution and cromolyn eye drops resulted in disappearance of her complaints.
